研究業績

2023年

  • PMID: 37777633 
    A possible role for proinflammatory activation via cGAS-STING pathway in atherosclerosis induced by accumulation of DNA double-strand breaks.
    Sakai C, Ueda K, Goda K, Fujita R, Maeda J, Nakayama S, Sotomaru Y, Tashiro S, Yoshizumi M, Ishida T, Ishida M.
    Sci Rep. 2023 Sep 30;13(1):16470.
    doi: 10.1038/s41598-023-43848-7.
  • PMID: 36634373 
    Klotho protects chromosomal DNA from radiation-induced damage.
    Nakayama S, Sun J, Horikoshi Y, Kamimura Y, Ike T, Fujino S, Kinugasa Y, Sasaki K, Nakashima A, Masaki T, Tashiro S.
    J Biochem. 2023 Apr 26;173(5):375-382.
    doi: 10.1093/jb/mvad001.
  • PMID: 37015790 
    Impact of lifting the mandatory evacuation order after the Fukushima Daiichi Nuclear Power Plant accident on the emergency medical system: a retrospective observational study at Minamisoma City with machine learning analysis.
    Yoshimura H, Yamamoto C, Sawano T, Nishikawa Y, Saito H, Nonaka S, Zhao T, Ito N, Tashiro S, Ozaki A, Oikawa T, Tsubokura M..
    BMJ Open. 2023 Apr 4;13(4):e067536.
    doi: 10.1136/bmjopen-2022-067536.
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2022年

  • PMID: 36598778 
    Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway -Application to a biomarker for atherosclerosis.
    Ueda K, Sakai C, Ishida T, Morita K, Kobayashi Y, Horikoshi Y, Baba A, Okazaki Y, Yoshizumi M, Tashiro S, Ishida M.
    Clin Sci (Lond). 2023 Jan 31;137(2):163-180.
    doi: 10.1042/CS20220525.
  • PMID: 35650148 
    A DNA Damage Induced by Radiation Exposure from Cardiac Catheterization.
    Jin Y, Yaegashi D, Shi L, Ishida M, Sakai C, Yokokawa T, Abe Y, Sakai A, Yamaki T, Kunii H, Nakazato K, Hijioka N, Awai K, Tashiro S, Takeishi Y, Ishida T.
    Int Heart J. 2022;63(3):466-475.
    doi: 10.1536/ihj.22-037.
  • PMID: 35090038 
    A Combination of Iohexol Treatment and Ionizing Radiation Exposure Enhances Kidney Injury in Contrast-Induced Nephropathy by Increasing DNA Damage.
    Fujino S, Sun J, Nakayama S, Horikoshi Y, Kinugasa Y, Ishida M, Sakai C, Ike T, Doi S, Masaki T, Tashiro S.
    Radiat Res. 2022 Apr 1;197(4):384-395.
    doi: 10.1667/RADE-21-00178.1.
  •  
  • 低線量放射線の生体影響
    田代 聡、衣笠 泰葉
    生体の科学 医学書院 第73巻第2号2022年4月15日発行 154-157

2021年

  • PMID: 34977921 
    Biological and internal dosimetry for radiation medicine: current status and future perspectives.
    Sudprasert W, Belyakov OV, Tashiro S.
    J Radiat Res. 2022 Mar 17;63(2):247-254.
    doi: 10.1093/jrr/rrab119.
  • PMID: 34337769 
    Piwi-piRNA complexes induce stepwise changes in nuclear architecture at target loci.
    Iwasaki YW, Sriswasdi S, Kinugasa Y, Adachi J, Horikoshi Y, Shibuya A, Iwasaki W, Tashiro S, Tomonaga T, Siomi H.
    EMBO J. 2021 Aug 2:e108345.
    doi: 10.15252/embj.2021108345. Epub 2021 Aug 2.
  • PMID: 34226518 
    OASIS/CREB3L1 is a factor that responds to nuclear envelope stress.
    Kamikawa Y, Saito A, Matsuhisa K, Kaneko M, Asada R, Horikoshi Y, Tashiro S, Imaizumi K.
    Cell Death Discov. 2021 Jun 29;7(1):152.
    doi: 10.1038/s41420-021-00540-x.
  • PMID: 34109803 
    Lessons from the Fukushima Daiichi nuclear power plant accident -from a research perspective.
    Tashiro S.
    Ann ICRP. 2021 Jun 10:1466453211015394.
    doi: 10.1177/01466453211015394.
  • PMID: 33870130 
    Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and associated clonal evolution.
    Matsuno Y, Hyodo M, Suzuki M, Tanaka Y, Horikoshi Y, Murakami Y, Torigoe H, Mano H, Tashiro S, Yoshioka KI.
    iScience. 2021 Mar 15;24(4):102313.
    doi: 10.1016/j.isci.2021.102313. eCollection 2021 Apr 23.
  • PMID: 33400798 
    Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients.
    Imano N, Nishibuchi I, Kawabata E, Kinugasa Y, Shi L, Sakai C, Ishida M, Sakane H, Akita T, Ishida T, Kimura T, Murakami Y, Tanaka K, Horikoshi Y, Sun J, Nagata Y, Tashiro S.
    Radiat Res, 2021 Mar 1; 195 (3): 244–252.
    doi.org/10.1667/RADE-20-00234.1
  • 低線量CT被ばくの人体影響
    田代 聡、坂根 寛晃、粟井 和夫
    アイソトープニュース 776巻 2021年8月号 29-31
  •  

2020年

  • PMID: 33373621 
    Bach1 Plays an Important Role in Angiogenesis Through Regulation of Oxidative Stress
    Yusoff FM, Maruhashi T, Kawano K, Nakashima A, Chayama K, Tashiro S, Igarashi K, Higashi Y.
    Microvasc Res. 2021 Mar;134:104126.
    doi: 10.1016/j.mvr.2020.104126.
  • PMID: 30930412 
    DNA Damage and Senescence-Associated Inflammation in Cardiovascular Disease
    Ishida T, Ishida M, Tashiro S, Takeishi Y.
    Biol Pharm Bull. 2019;42(4):531-537.
    doi: 10.1248/bpb.b18-00865.
  • PMID: 32154776
    Biological Effects of Low-Dose Chest CT on Chromosomal DNA
    Sakane H, Ishida M, Shi L, Fukumoto W, Sakai C, Miyata Y, Ishida T, Akita T, Okada M, Awai K, Tashiro S.
    Radiology, 2020 May;295(2):439-445.
    doi: 10.1148/radiol.2020190389. Epub 2020 Mar 10.

2019年

  • 放射線被ばくによる染色体異常
    田代 聡
    日本整形外科学会誌 93巻10号,2019年(令和元年)10月25日発行 769-773
  • 放射線被ばくによるDNA損傷と染色体異常
    坂根 寛晃、田代 聡
    臨床整形外科 第54巻 第4号 2019年4月25日発行 392-395
  • PMID: 31509522
    Role of dynamic nuclear deformation on genomic architecture reorganization.
    Seirin-Lee S, Osakada F, Takeda J, Tashiro S, Kobayashi R, Yamamoto T, Ochiai H.
    PLoS Comput Biol. 2019 Sep 11;15(9):e1007289.
    doi: 10.1371/journal.pcbi.1007289. eCollection 2019 Sep.
  • PMID: 31119278
    Matrin3 promotes homologous recombinational repair by regulation of RAD51 
    Shi L, Sun J, Kinomura A, Fukuto A, Horikoshi Y, Tashiro S.
    J Biochem. October 2019; 166(4): 343–351
    doi: 10.1093/jb/mvz041.
  • PMID: 30930412
    DNA Damage and Senescence-Associated Inflammation in Cardiovascular Disease.
    Ishida T, Ishida M, Tashiro S, Takeishi Y.
    Biol Pharm Bull. 2019;42(4):531-537. doi: 10.1248/bpb.b18-00865. Review.

2018年

  • PMID: 30053102
    Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
    Arimura Y, Ikura M, Fujita R, Noda M, Kobayashi W, Horikoshi N, Sun J, Shi L, Kusakabe M, Harata M, Ohkawa Y, Tashiro S, Kimura H, Ikura T, Kurumizaka H.
    Nucleic Acids Res. 2018 Nov 2;46(19):10007-10018. doi: 10.1093/nar/gky661.
  • PMID: 30040044
    Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure.
    Shi L, Fujioka K, Sakurai-Ozato N, Fukumoto W, Satoh K, Sun J, Awazu A, Tanaka K, Ishida M, Ishida T, Nakano Y, Kihara Y, Hayes CN, Aikata H, Chayama K, Ito T, Awai K, Tashiro S.
    Radiat Res. 2018 Oct;190(4):424-432. doi: 10.1667/RR14976.1. Epub 2018 Jul 24.
  • PMID: 29036656
    Relative Biological Effectiveness of Neutrons Derived from the Excess Relative Risk Model with the Atomic Bomb Survivors data Managed by Hiroshima University. Satoh K, Yasuda H, Kawakami H, Tashiro S.
    Radiat Prot Dosimetry. 2018 Aug 1;180(1-4):346-350. doi: 10.1093/rpd/ncx173.
  • PMID: 29759113
    Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations.
    Sun J, Shi L, Kinomura A, Fukuto A, Horikoshi Y, Oma Y, Harata M, Ikura M, Ikura T, Kanaar R, Tashiro S.
    Elife. 2018 May 8;7. pii: e32222. doi: 10.7554/eLife.32222.
  • PMID: 29626209
    XRCC3 polymorphism is associated with hypertension-induced left ventricular hypertrophy.
    Ariyandy A, Sakai C, Ishida M, Mizuta R, Miyagawa K, Tashiro S, Kinomura A, Hiraaki K, Ueda K, Yoshizumi M, Ishida T.
    Hypertens Res. 2018 Jun;41(6):426-434. doi: 10.1038/s41440-018-0038-0. Epub 2018 Apr 6. Review.
  • PMID: 29528422
    Exploration of genetic basis underlying individual differences in radiosensitivity within human populations using genome editing technology.
    Miyamoto T, Akutsu SN, Tauchi H, Kudo Y, Tashiro S, Yamamoto T, Matsuura S.
    J Radiat Res. 2018 Apr 1;59(suppl_2):ii75-ii82.  doi: 10.1093/jrr/rry007.
  • PMID: 29518207
    Estimation of the effects of medical diagnostic radiation exposure based on DNA damage.
    Shi L, Tashiro S.
    J Radiat Res. 2018 Apr 1;59(suppl_2):ii121-ii129.
    doi: 10.1093/jrr/rry006.
  • PMID: 29095668
    SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites.
    Fukuto A, Ikura M, Ikura T, Sun J, Horikoshi Y, Shima H, Igarashi K, Kusakabe M, Harata M, Horikoshi Y, Kurumizaka H, Kiuchi Y, Tashiro S.
    Nucleus. 2018 Jan 1;9(1):87-94.
    doi: 10.1080/19491034.2017.1395543. Epub 2017 Dec 14.
  • 放射線と染色体異常
    田代 聡
    実験医学 Vol.36 No.27 (増刊) 192-196 2018年11月1日発行
  • 放射線災害と子ども
    田代 聡
    小児内科 2018 50:411-413
  • CTにおける被ばくの生物学的影響
    福本 航、石田万理、田代 聡
    最新Body CT診断 84-90 (総ページ数380)
    編集 粟井和夫、陣崎雅弘
    2018年3月 メディカル・サイエンス・インターナショナル社
    ISBN 978-4-89592-907-3
  • ヌクレオームコンソーシアム
    田代 聡、木村 宏
    生物物理 2018

2017年

  • PMID: 28729543
    Evaluation of ATM heterozygous mutations underlying individual differences in radiosensitivity using genome editing in human cultured cells.
    Royba E, Miyamoto T, Natsuko Akutsu S, Hosoba K, Tauchi H, Kudo Y, Tashiro S, Yamamoto T, Matsuura S.
    Sci Rep. Scientific Reports.  2017 Jul 20;7(1):5996. doi: 10.1038/s41598-017-06393-8.
  • PMID: 27510626
    DNA damage in lymphocytes induced by cardiac CT and comparison with physical exposure parameters.
    Fukumoto W, Ishida M, Sakai C, Tashiro S, Ishida T, Nakano Y, Tatsugami F, Awai K.
    Eur Radiol. European Radiology. 2017 Apr;27(4):1660-1666. doi:10.1007/s00330-016-4519-8.
  • PMID: 27241726
    A New Application of the Phase-field Method for Understanding the Reorganization Mechanisms of  Nuclear Architecture.
    Seirin Lee A, Tashiro S, Awazu A, Kobayashi R. 
    Journal of Mathematical Biology. 2017 Jan;74(1-2):333-354 
    doi: 10.1007/s00285-016-1031-3

2016年

  • PMID: 27616329
    Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse.
    Nishino T, Matsunaga R, Jikihara H, Uchida M, Maeda A, Qi G, Abe T, Kiyonari H, Tashiro S, Inagaki-Ohara K, Shimamoto F, Konishi H.
    Biochim Biophys Acta. 2016 Nov;1861(11):1816-1827. doi:10.1016/j.bbalip.2016.09.006.
  • PMID: 27015828
    Cytogenetic effects of radioiodine therapy: a 20-year follow-up study.
    Livingston GK, Khvostunov IK, Gregoire E, Barquinero JF, Shi L, Tashiro S.
    Radiat Environ Biophys. 2016 May;55(2):203-13. doi: 10.1007/s00411-016-0647-4.
  • PMID: 26825989
    Enhanced gefitinib-induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia-mutated kinase inhibition in non-small-cell lung cancer cells.
    Misumi K, Sun J, Kinomura A, Miyata Y, Okada M, Tashiro S.
    Cancer Sci. 2016 Apr;107(4):444-51. doi:10.1111/cas.12899.
  • PMID: 26757249
    Relaxed Chromatin Formation and Weak Suppression of Homologous Pairing by the Testis-Specific Linker Histone H1T.
    Machida S, Hayashida R, Takaku M, Fukuto A, Sun J, Kinomura A, Tashiro S, Kurumizaka H.
    Biochemistry. 2016 Feb 2;55(4):637-46. 
    doi: 10.1021/acs.biochem.5b01126.
  • PMID: 26729854
    Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current.
    Nakano Y, Ochi H, Onohara Y, Toshishige M, Tokuyama T, Matsumura H, Kawazoe H, Tomomori S, Sairaku A, Watanabe Y, Ikenaga H, Motoda C, Suenari K, Hayashida Y, Miki D, Oda N, Kishimoto S, Oda N, Yoshida Y, Tashiro S, Chayama K, Kihara Y.
    Circ Arrhythm Electrophysiol. 2016 Jan;9(1):e003436. 
    doi:10.1161/CIRCEP.115.003436.

2015年

  • PMID: 26123175
    hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair.
    Okimoto S, Sun J, Fukuto A, Horikoshi Y, Matsuda S, Matsuda T, Ikura M, Ikura T, Machida S, Kurumizaka H, Miyamoto Y, Oka M, Yoneda Y, Kiuchi Y, Tashiro S.
    Genes Cells. 2015 Sep;20(9):681-94. doi: 10.1111/gtc.12262. Epub 2015 Jun 30.
  • PMID: 25799058
    Structural basis for ubiquitin recognition by ubiquitin-binding zinc finger of FAAP20.
    Toma A, Takahashi TS, Sato Y, Yamagata A, Goto-Ito S, Nakada S, Fukuto A, Horikoshi Y, Tashiro S, Fukai S.
    PLoS One. 2015 Mar 23;10(3):e0120887. doi: 10.1371/journal.pone.0120887. eCollection 2015.
  • PMID: 25738524
    The International Nucleome Consortium.
    Tashiro S, Lanctôt C.
    Nucleus. 2015;6(2):89-92. doi:10.1080/19491034.2015.1022703.
  • PMID: 25733566
    Regulation of homologous recombinational repair by lamin B1 in radiation-induced DNA damage.
    Liu NA, Sun J, Kono K, Horikoshi Y, Ikura T, Tong X, Haraguchi T, Tashiro S.
    FASEB J. 2015;29(6):2514-25. doi:10.1096/fj.14-265546.

2014年

  • PMID: 25344725
    The transcription repressors Bach2 and Bach1 collaborate with EBF1 to promote B cell development by curbing myeloid program.
    Ari Itoh-Nakadai, Reina Hikota, Akihiko Muto, Kohei Kometani, Miki Matsui-Watanabe, Yuki Sato, Masahiro Kobayashi, Atsushi Nakamura, Yuichi Miura, Yoko Yano, Satoshi Tashiro, Jiying Sun, Tomokatsu Ikawa, Tomohiro Kurosaki, Kyoko Ochiai, and Kazuhiko Igarashi.
    Nature Immunology. 2014;15(12):1171-80.
    doi: 10.1038/ni.3024.
  • PMID: 25093845
    Smoking cessation reverses DNA double-strand breaks in human mononuclear  cells.
    Ishida M, Ishida T, Tashiro S, Uchida H, Sakai C, Hironobe N, Miura K, Hashimoto Y,Arihiro K, Chayama K, Kihara Y, Yoshizumi M.
    PLoS One. 2014 Aug 5;9(8):e103993. doi: 10.1371/journal.pone.0103993. eCollection 2014.
  • PMID: 24969791
    Reorganization of damaged chromatin by the exchange of histone variant H2A.Z-2.
    Nishibuchi I, Suzuki H, Kinomura A, Sun J, Liu NA, Horikoshi Y, Shima H,Kusakabe M, Harata M, Fukagawa T, Ikura T, Ishida T, Nagata Y, Tashiro S.
    Int J Radiat Oncol Biol Phys. 2014 Jul 15;89(4):736-44.
    doi: 10.1016/j.ijrobp.2014.03.031.
  • PMID: 24798879
    Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1.
    Machida S, Takaku M, Ikura M, Sun J, Suzuki H, Kobayashi W, Kinomura A, Osakabe A, Tachiwana H, Horikoshi Y, Fukuto A, Matsuda R, Ura K, Tashiro S, Ikura T, Kurumizaka H.
    Sci Rep. 2014 May 6;4:4863. doi: 10.1038/srep04863.
  • PMID: 24334614
    Role of DNA damage in cardiovascular disease.
    Ishida T, Ishida M, Tashiro S, Yoshizumi M, Kihara Y.
    Circ J. 2014;78(1):42-50. Epub 2013 Dec 12. Review.
    doi: 10.1253/circj.cj-13-1194.

2013年

  • PMID: 24046452
    Activation of the SUMO modification system is required for the accumulation of RAD51 at sites containing DNA damage.
    Shima H, Suzuki H, Sun J, Kono K, Shi L, Kinomura A, Horikoshi Y, Ikura T, Ikura M, Kanaar R, Igarashi K, Saitoh H, Kurumizaka H, Tashiro S
    J Cell Sci. 2013;126(Pt 22):5284-92.
    doi: 10.1242/jcs.133744.
  • PMID: 24033642
    Involvement of homologous recombination in the synergism between cisplatin and poly(ADP-ribose) polymerase inhibition.
    Sakogawa K, Aoki Y, Misumi K, Hamai Y, Emi M, Hihara J, Shi L, Kono K, Horikoshi Y, Sun J, Ikura T, Okada M, Tashiro S.
    Cancer Sci. 2013;104(12):1593-9. doi: 10.1111/cas.12281. Epub 2013 Oct 10.
  • PMID: 23588527
    Involvement of ribonucleotide reductase-M1 in 5-fluorouracil-induced DNA damage in esophageal cancer cell lines.
    Aoki Y, Sakogawa K, Hihara J, Emi M, Hmamai Y, Kono K, Shi L, Sun J, Kitao H, Ikura T, Niida H, Nakanishi M, Okada M, Tashiro S.
    Int J Oncol 2013 Jun;42(6):1951-60. doi: 10.3892/ijo.2013.1899. Epub 2013 Apr 16.
  • PMID: 23652004
    A functional deficiency of TERA/VCP/p97 contributes to impaired DNA damage repair in multiple polyglutamine diseases.
    Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Sishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H
    Nature commun 2013;4:1816. doi: 10.1038/ncomms2828.
  • PMID: 23593010
    A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation.
    Nakano Y, Chayama K, Ochi H, Toshishige M, Hayashida Y, Miki D, Hayes CN, Suzuki H, Tokuyama T, Oda N, Suenari K, Uchimura-Makita Y, Kajihara K, Sairaku A, Motoda C, Fujiwara M, Watanabe Y, Yoshida Y, Ohkubo K, Watanabe I, Nogami A, Hasegawa K, Watanabe H, Endo N, Aiba T, Shimizu W, Ohno S, Horie M, Arihiro K, Tashiro S, Makita N, Kihara Y.
    PLoS Genet. 2013; 9: e1003364. doi: 10.1371/journal.pgen.1003364

2012年

  • PMID: 22509803
    A Modified System for Analyzing Ionizing Radiation-Induced Chromosome Abnormalities.
    Shi L, Fujioka K, Sun J, Kinomura A, Inaba T, Ikura T, Ohtaki M, Yoshida M, Kodama Y, Livingston GK, Kamiya K, Tashiro S.
    Radiat Res. 2012 May;177(5):533-8. doi: 10.1667/rr2849.1. Epub 2012 Apr 17.
  • PMID: 22302183
    Investigation on circular asymmetry of geographical distribution in cancer mortality of Hiroshima atomic bomb survivors based on risk maps: analysis of spatial survival data.
    Tonda T, Satoh K, Otani K, Sato Y, Maruyama H, Kawakami H, Tashiro S, Hoshi M, Ohtaki M.
    Radiat Environ Biophys. 2012; 51(2):133-141. doi: 10.1007/s00411-012-0402-4.

2011年

  • PMID: 22116401
    Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2.
    Hosoya N, Okajima M, Kinomura A, Fujii Y, Hiyama T, Sun J, Tashiro S, Miyagawa K.
    EMBO Rep. 2011 Dec 23;13(1):44-51. doi: 10.1038/embor.2011.221.
  • PMID: 21375680
    Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51.
    Takaku M, Kainuma T, Ishida-Takaku T, Ishigami S, Suzuki H, Tashiro S, van Soest RW, Nakao Y, Kurumizaka H.
    Genes Cells. 2011 Apr;16(4):427-36.
    doi: 10.1111/j.1365-2443.2011.01494.x. Epub 2011 Mar 6.
  • PMID: 21362551
    Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein.
    Katoh Y, Ikura T, Hoshikawa Y, Tashiro S, Ito T, Ohta M, Kera Y, Noda T, Igarashi K.
    Mol Cell. 2011 Mar 4;41(5):554-66. doi: 10.1016/j.molcel.2011.02.018.
  • PMID: 21362548
    Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.
    Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, Oliveira DV, Shimada M, Tauchi H, Suzuki H, Tashiro S, Zou L, Komatsu K.
    Mol Cell. 2011 Mar 4;41(5):515-28. doi: 10.1016/j.molcel.2011.02.002.

2010年

  • PMID: 21048951
    ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.
    Sun J, Oma Y, Harata M, Kono K, Shima H, Kinomura A, Ikura T, Suzuki H, Mizutani S, Kanaar R, Tashiro S.
    PLoS One. 2010 Oct 27;5(10):e13554. doi: 10.1371/journal.pone.0013554.
  • PMID: 20953163
    Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.
    Muto A, Ochiai K, Kimura Y, Itoh-Nakadai A, Calame KL, Ikebe D, Tashiro S, Igarashi K.
    EMBO J. 2010 Dec 1;29(23):4048-61. doi: 10.1038/emboj.2010.257. Epub 2010 Oct 15.
  • PMID: 20623582
    p130Cas, Crk-associated substrate plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration.
    Tazaki T, Sasaki T, Uto K, Yamasaki N, Tashiro S, Sakai R, Tanaka M, Oda H, Honda Z, Honda H.
    Hepatology. 2010 Sep;52(3):1089-99. doi: 10.1002/hep.23767.
  • PMID: 20190268
    The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site.
    Saito K, Kagawa W, Suzuki T, Suzuki H, Yokoyama S, Saitoh H, Tashiro S, Dohmae N, Kurumizaka H.
    J Biochem. 2010 Jun;147(6):833-42. doi: 10.1093/jb/mvq020. Epub 2010 Feb 27.
  • PMID: 20159953
    Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase.
    Niida H, Katsuno Y, Sengoku M, Shimada M, Yukawa M, Ikura M, Ikura T, Kohno K, Shima H, Suzuki H, Tashiro S, Nakanishi M.
    Genes Dev. 2010 Feb 15;24(4):333-8. doi: 10.1101/gad.1863810.

2009年

  • PMID: 19338747
    Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.
    Kobayashi J, Tauchi H, Chen B, Burma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K.
    Biochem Biophys Res Commun. 2009 Mar 20;380(4):752-7. doi: 10.1016/j.bbrc.2009.01.109. Epub 2009 Jan 23.
  • PMID: 19336413
    DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange.
    Ishida T, Takizawa Y, Kainuma T, Inoue J, Mikawa T, Shibata T, Suzuki H, Tashiro S, Kurumizaka H.
    Nucleic Acids Res. 2009 Jun;37(10):3367-76. doi: 10.1093/nar/gkp200. Epub 2009 Mar 30.
  • PMID: 19014934
    The human actin-related protein hArp5: nucleo-cytoplasmic shuttling and involvement in DNA repair.
    Kitayama K, Kamo M, Oma Y, Matsuda R, Uchida T, Ikura T, Tashiro S, Ohyama T, Winsor B, Harata M.
    Exp Cell Res. 2009 Jan 15;315(2):206-17. doi: 10.1016/j.yexcr.2008.10.028. Epub 2008 Nov 5.

2008年

  • PMID: 18931676
    FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.
    Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita-Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M.
    Nat Struct Mol Biol. 2008 Nov;15(11):1138-46. doi: 10.1038/nsmb.1504. Epub 2008 Oct 19.
  • PMID: 18555605
    Regulation of heme oxygenase-1 by transcription factor Bach1 in the mouse brain.
    Sakoda E, Igarashi K, Sun J, Kurisu K, Tashiro S.
    Neurosci Lett. 2008 Aug 1;440(2):160-5. doi: 10.1016/j.neulet.2008.04.082. Epub 2008 Apr 26.
  • PMID: 18456231
    Morphologic effects of epithelial ion channels on the mouse uterus: differences between raloxifene analog (LY117018) and estradiol treatments.
    Nobuzane T, Tashiro S, Kudo Y.
    Am J Obstet Gynecol. 2008 Oct;199(4):363.e1-6. doi: 10.1016/j.ajog.2008.03.047. Epub 2008 May 5.
  • PMID: 18201693
    The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification.
    Kono K, Harano Y, Hoshino H, Kobayashi M, Bazett-Jones DP, Muto A, Igarashi K, Tashiro S.
    Exp Cell Res. 2008 Feb 15;314(4):903-13. doi: 10.1016/j.yexcr.2007.12.013. Epub 2007 Dec 23.

2007年

  • PMID: 17709392
    DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics.
    Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R, Yoder K, Izumi S, Kuraoka I, Tanaka K, Kimura H, Ikura M, Nishikubo S, Ito T, Muto A, Miyagawa K, Takeda S, Fishel R, Igarashi K, Kamiya K.
    Mol Cell Biol. 2007 Oct;27(20):7028-40. doi: 10.1128/MCB.00579-07. Epub 2007 Aug 20.
  • PMID: 17383980
    Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression.
    Hoshino, H., Nishino, T.G., Tashiro, S., Miyazaki, M., Igarashi, K., Horinouchi, S., and Yoshida, M.
    J. Biochem. 2007 May;141(5):719-27. doi: 10.1093/jb/mvm073. Epub 2007 Mar 23.
  • PMID: 17044046
    Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemia cells.
    Ono, A., Kono, K., Ikebe, D., Muto, A., Sun, J., Kobayashi, M., Ueda, K., Melo, J. V., Igarashi, K., and Tashiro, S.
    Genes, Chromosomes & Cancer 2007 Jan;46(1):67-74. doi: 10.1002/gcc.20390.
  • PMID: 17227473
    Non-SCN5A related Brugada syndromes: verification of normal splicing and trafficking of SCN5A without exonic mutations.
    Nakano Y, Tashiro S, Kinoshita E, Kinoshita-Kikuta E, Takenaka S, Miyoshi M, Ogi H, Sakoda E, Oda N, Suenari K, Tonouchi Y, Okimoto T, Hirai Y, Miura F, Yamaoka K, Koike T, Chayama K.
    Ann Hum Genet. 2007 Jan;71(Pt 1):8-17. Erratum in: Ann Hum Genet. 2007 Jul;71(Pt 4):560.
    doi: 10.1111/j.1469-1809.2006.00297.x.

2006年

  • PMID: 17046816
    Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells.
    Ochiai K, Katoh Y, Ikura T, Hoshikawa Y, Noda T, Karasuyama H, Tashiro S, Muto A, Igarashi K.
    J Biol Chem. 2006 Dec 15;281(50):38226-34. Epub 2006 Oct 17.
    doi: 10.1074/jbc.M607592200.
  • PMID: 16356476
    Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes.
    Fujiwara T, Harigae H, Takahashi S, Furuyama K, Nakajima O, Sun J, Igarashi K,    Yamamoto M, Sassa S, Kaku M, Sasaki T. 
    Biochem Biophys Res Commun. 2006 Feb 3;340(1):105-10.
    doi: 10.1016/j.bbrc.2005.11.163. Epub 2005 Dec 7.
  • PMID: 16487038
    Heme oxygenase-1 gene enhancer manifests silencing activity in a chromatin environment prior to oxidative stress.
    Dohi Y, Alam J, Yoshizumi M, Sun J, Igarashi K
    Antioxid Redox Signal. Jan-Feb 2006;8(1-2):60-7. doi: 10.1089/ars.2006.8.60.
  • PMID: 16487043
    The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation (Review).
    Igarashi K, Sun J.
    Antioxid Redox Signal. Jan-Feb 2006;8(1-2):107-18. doi: 10.1089/ars.2006.8.107.
  • DNA修復とクロマチン構造変換.
    井倉 毅、田代 聡
    蛋白質核酸酵素 51(4):310-4.2006.
  • 白血病のゲノム不安定性.
    田代 聡、孫 継英.
    日本臨床 65(増刊号1)105-8.2006.
  • マルチカラー技術を用いたFISH法と免疫蛍光染色.
    田代 聡、島 弘季.
    蛋白質核酸酵素 51(4):1978-1980.2006.
  • ゲノム修復と細胞核ダイナミクス.
    田代 聡、島 弘季、孫 継英.
    放射線生物研究 41(2): 182-195.2006.

2005年

  • PMID: 15809329
    Dynamic Cytoplasmic Anchoring of the Transcription Factor Bach1 by Intracellular Hyaluronic Acid Binding Protein IHABP.
    Yamasaki C, Tashiro S, Nishito Y, Sueda T, Igarashi K.
    J Biochem. 2005 Mar;137(3):287-96. doi: 10.1093/jb/mvi031.
  • PMID: 15728456
    Polycomb group gene mel-18 regulates early T progenitor expansion by maintaining the expression of Hes-1, a target of the notch pathway.
    Miyazaki M, Kawamoto H, Kato Y, Itoi M, Miyazaki K, Masuda K, Tashiro S, Ishihara H, Igarashi K, Amagai T, Kanno R, Kanno M.
    J Immunol. 2005 Mar 1;174(5):2507-16. doi: 10.4049/jimmunol.174.5.2507.
  • PMID: 15613547
    Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment. Blood.
    Toki T, Katsuoka F, Kanezaki R, Xu G, Kurotaki H, Sun J, Kamio T, Watanabe S, Tandai S, Terui K, Yagihashi S, Komatsu N, Igarashi K, Yamamoto M, Ito E.
    Blood. 2005 Apr 15;105(8):3100-8.
    doi: 10.1182/blood-2004-07-2826. Epub 2004 Dec 21.
  • 分子標的療法薬imatinibによる慢性骨髄性白血病治療とその問題点.
    小野 厚、五十嵐和彦、田代 聡
    健康管理と臨床検査.(神部眞之、渡辺清明編),pp247-250,2005.

2004年

  • PMID: 15464985
    Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells.
    Tahara T, Sun J, Igarashi K, Taketani S.
    Biochem Biophys Res Commun. 2004 Nov 5;324(1):77-85.
    doi: 10.1016/j.bbrc.2004.09.022.
  • PMID: 15496594
    Role of the heme regulatory motif in the heme-mediated inhibition of mitochondrial import of 5-aminolevulinate synthase.
    Munakata H, Sun JY, Yoshida K, Nakatani T, Honda E, Hayakawa S, Furuyama K, Hayashi N.  J J Biochem. 2004 Aug;136(2):233-8.
    doi: 10.1093/jb/mvh112.
  • PMID: 15152264
    The transcriptional programme of antibody class switching involves the repressor Bach2.
    Muto, A., Tashiro, S., Nakajima, O., Hoshino, H., Takahashi, S., Sakoda, E., Ikebe, D., Yamamoto, M., and Igarashi, K.
    Nature. 2004 Jun 3;429(6991):566-71. doi: 10.1038/nature02596.  Epub 2004 May 19.
  • PMID: 15175654
    Heme regulates gene expression by triggering Crm1-dependent nuclear  export of Bach1.
    Suzuki, H., Tashiro, S., Hira, S., Sun, J., Yamazaki, C., Zenke, Y., Ikeda-Saito, M., Yoshida, M., and Igarashi, K.
    EMBO J. 2004 Jul 7;23(13):2544-53. doi: 10.1038/sj.emboj.7600248. Epub 2004 Jun 3.
  • PMID: 15060166
    Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2.
    Tashiro, S., Muto, A., Tanimoto, K., Tsuchiya, H., Suzuki, H., Hoshino,  H., Yoshida, M., Walter, J., and Igarashi,  K.
    Mol Cell Biol. 2004 Apr;24(8):3473-84. doi: 10.1128/mcb.24.8.3473-3484.2004.
  • PMID: 14747657
    Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network. 
    Sun, J., Brand, M., Zenke, Y., Tashiro, S., Groudine, M. and Igarashi,  K.
    Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1461-6. doi: 10.1073/pnas.0308083100. Epub 2004 Jan 27.
  • PMID: 14660636
    Heme positively regulates the expression  of β-globin at the locus 
    Tahara, T., Sun, J., Nakanishi, K., Yamamoto, M., Mori, H., Saito, T.,  Fujita, H., Igarashi, K., and Taketani, S.
    control region via the transcription  factor Bach1 in erythroid cells.
    J. Biol. Chem. 279, 5480-5487  (2004)
    doi: 10.1074/jbc.M302733200.
  • PMID: 14749735
    XRCC3 deficiency results in a defect in recombination and increased
    endoreduplication in human cells.
    Yoshihara T, Ishida M, Kinomura A, Katsura M, Tsuruga T, Tashiro S, Asahara T, Miyagawa K.
    EMBO J. 2004 Feb 11;23(3):670-80. doi: 10.1038/sj.emboj.7600087. Epub 2004 Jan 29.
  • 酸化ストレスにより転写因子Bach2はPMLボディ周辺の遺伝子発現を特異的に抑制する.
    田代 聡、五十嵐和彦
    実験医学 22(15): 2164-2166, 2004.
  • 染色体DNAの分子イメージング.
    田代 聡
    細胞核のダイナミクス.竹安邦夫.米田悦啓編 pp19-22.Springer.2004.

2003年

  • PMID: 12588523
    A new system for laser-UVA-microirradiation of living cells.
    Walter J., Cremer T., Miyagawa  K., Tashiro S. 
    J Microsc. 209:71-75, (2003)
    doi: 10.1046/j.1365-2818.2003.01117.x.
  • PMID: 12604593
    Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages.
    Walter J., Schermelleh L., Cremer M., Tashiro S., Cremer T. 
    J Cell Biol. 2003 Mar 3;160(5):685-97. doi: 10.1083/jcb.200211103. Epub 2003 Feb 25.
  • PMID: 14504288
    Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene.
    Suzuki, H., Tashiro, S.,  Sun, J., Doi, H., Satomi, S. and Igarashi, K. 
    J Biol Chem. 2003 Dec 5;278(49):49246-53. doi: 10.1074/jbc.M306764200.  Epub 2003 Sep 22.
  • PMID: 12511571
    Bach 1 functions as a hypoxia-inducible  repressor for the heme oxygenase-1 gene in human cells.
    Kitamuro, T., Takahashi, K., Ogawa, K., Udono, R.F., Takeda, K., Furuyama, K., Nakayama, M., Sun J., Fujita, H., Hida, W., Hattori, T., Shirato, K., Igarashi, K., Shibahara, S.
    J. Biol. Chem. 278, 9125-9133  (2003)
    doi: 10.1074/jbc.M209939200.

2002年

  • PMID: 12356737
    Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene.
    Sun, J., Hoshino, H., Takaku, K., Nakajima, O., Muto, A., Suzuki, H., Tashiro, S., Takahashi, S., Shibahara, S., Alam, J., Taketo, M. M., Yamamoto, M. and Igarashi, K.
    EMBO J. 2002 Oct 1;21(19):5216-24.  doi: 10.1093/emboj/cdf516.
  • PMID: 11923289
    Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with PML nuclear bodies.
    Muto, A., Tashiro, S., Tsuchiya, H., Kume, A., Kanno, M., Ito, E., Yamamoto, M., and Igarashi, K.
    J Biol Chem. 2002 Jun 7;277(23):20724-33. doi: 10.1074/jbc.M112003200.  Epub 2002 Mar 28.
  • PMID: 11782437
    A role for RAD54B in homologous recombination in human cells.
    Miyagawa, K., Tsuruga, T., Kinomura, A., Usui, K., Katsura, M., Tashiro, S., Mishima, H., Tanaka, K.
    EMBO J. 2002 Jan 15;21(1-2):175-80. doi: 10.1093/emboj/21.1.175.
  • 核高次構造と核機能:染色体領域―クロマチン間領域モデルを中心として.
    田代 聡、小野 厚、五十嵐和彦
    細胞工学 10:1154-1156,2002.

2001年

  • PMID: 11530014
    The Promoter of Mouse Transcription Repressor bach1 is Regulated by Sp1 and Trans-Activated  by Bach1.
    Sun, J., Muto, A., Hoshino, H., Kobayashi, A., Nishimura, S.,  Yamamoto, M., Hayashi, N., Ito, E., and Igarashi, K. 
    J. Biochem. 2001 Sep;130(3):385-92.
    doi: 10.1093/oxfordjournals.jbchem.a002997.
  • PMID: 11387216
    Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1.
    Ogawa K, Sun J, Taketani S, Nakajima O, Nishitani C, Sassa S, Hayashi N, Yamamoto M, Shibahara S, Fujita H, Igarashi K.
    EMBO J. 2001 Jun 1;20(11):2835-43.
    doi: 10.1093/emboj/20.11.2835.
  • DNA修復機構と核高次構造
    田代 聡
    遺伝子医学 5:73-77,2001.
  • ゲノムの高次構造と転写制御.
    五十嵐和彦、田代 聡
    遺伝子の構造と機能.山本雅之編 pp.1-10.共立出版.2001

2000年

  • PMID: 10908572
    Rad51 accumulation at sites of DNA damage and in postreplicative chromatin.
    Tashiro, S., Walter, J., Shinohara, A., Kamada, N., Cremer, T.
    J. Cell Biol., 150, 283-91,  (2000)
    doi: 10.1083/jcb.150.2.283.

1999年

  • PMID: 10446489
    Instability of chromosome 7 in colony forming cells of patients with aplastic anemia.
    Ueda H, Tashiro S, Kojima S, Tanaka K, Eguchi M, Ueda K, Kamada N
    Int J Hematol. 70: 13-19, (1999)

1996年

  • PMID: 8668342
    S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes.
    Tashiro S, Kotomura N, Shinohara A, Tanaka K, Ueda K, Kamada N
    Oncogene 12: 2165- 2170, (1996)

1995年

  • PMID: 7734351
    Emergence of karyotypically unrelated clone in remission of de novo acute myeloblastic leukaemias.
    Kudoh S, Asou H, Kyo T, Asaoku H, Dohy H, Eguchi M, Tashiro S, Tanaka K, Kamada N.
    Br J Haematol. 89, 531-534, (1995)

1994年

  • PMID: 8208541
    Identification of illegitimate recombination hot spot of the retinoic acid receptor alpha gene involved in 15;17 chromosome translocation of acute promyelocytic leukemia.
    Tashiro S, Wang Z, Kotomura N, Eguchi M, Niwa O, Ueda K, Kamada N
    Oncogene 9: 1939-1945, (1994)

1993年

  • PMID: 8385082
    Detection of PML/retinoic acid receptor alpha gene rearrangements by polymerase chain reaction usig genomic DNA in patients with acute promyelocytic leukemia.
    Tashiro S, Tanaka K, Asou H, Kyo T, Dohy H, Suzuki K, Kamada N
    Jpn.J.Cancer Res.84: 110-113, (1993)
    doi: 10.1111/j.1349-7006.1993.tb02841.x.
  • PMID: 8136271
    Japanese B cell chronic lymphocytic leukaemia: a cytogenetic and molecular biological study.
    Asou H, Takechi M, Tanaka K, Tashiro S, Dohy H, Ohno R, Kamada N.
    Br J Haematol. 85, 492-497, (1993)
    doi: 10.1111/j.1365-2141.1993.tb03338.x.

1992年

  • PMID: 1549371
    Cytogenetic 2;18 and 18;22 translocation in chronic lymphocytic leukemia with juxaposition of bcl-2 and immunoglobulin light chain genes.
    Tashiro S, Takechi M, Asou H, Takauchi K, Kyo T, Dohy H, Kikuchi M, Kamada N, Tsujimoto
    Oncogene 7: 573-577, (1992)
  • PMID: 1451059
    The prognostic value of cytogenetic analyses in patients with acute nonlymphocytic leukemia treated with the same intensive chemotherapy.
    Tashiro S, Kyo T, Tanaka K, Oguma N, Hashimoto T, Dohy H, Kamada N
    Cancer 70: 2809-2815, (1992)
    doi: 10.1002/1097-0142(19921215)70:12<2809::aid-cncr2820701214>3.0.co;2-#.

1991年

  • PMID: 2018839
    Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation.
    Asou H, Tashiro S, Hamamoto K, Otsuji A, Kita K, Kamada N.
    Blood 77: 2031-2036, (1991)